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The core of DNA Software's product line is it's computational environment, the Oligonucleotide Modeling PlatformTM (OMPTM). OMPTM is a programmable predictive modeling environment, which is used to develop customer-specific applications. OMPTM takes all of the chemical and biological knowledge and expertise developed by DNA Software scientists and Dr. SantaLucia's previous work, and encapsulates it into a single, simulation platform. Key technology features of OMPTM include:
- A defined scripting language, allowing OMP to be "programmed" for specific tasks necessary to users or client applications,
- Fully encapsulated hybridization science functions which precisely predict the DNA hybridization that will result from any specific oligo experiment under a variety different design conditions, including;
- Single-strand optimal and sub-optimal unimolecular structure prediction, recursive bimolecular hybridization algorithm,
- Customized numerical analysis code for the solution of multiple coupled hybridization equilibria,
- DNA secondary structure display,
- Display of species concentrations as a function of temperature,
- Interface with the sequence and annotation data in the SNP database,
- Interface with the Oracle, SQL and MS ACCESS database format,
- Rich modeling functionality, including capabilities to predict DNA microarray effectiveness, PCR and PCR multiplexed efficiency, and oligo probe and primer interactions (dimerization),
- A cutting edge peer-to-peer distributed computing architecture which allows OMPTM to run across a cluster or network of PCs, making OMPTM scalable and extremely fast,
- Cross-platform capability to run on most any commercial Windows, Linux, or Unix machine.
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