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  Innovative Solutions for Nucleic Acid Research

Oligonucleotide Modeling PlatformTM

 

The core of DNA Software's product line is it's computational environment, the Oligonucleotide Modeling PlatformTM (OMPTM).  OMPTM is a programmable predictive modeling environment, which is used to develop customer-specific applications.  OMPTM takes all of the chemical and biological knowledge and expertise developed by DNA Software scientists and Dr. SantaLucia's previous work, and encapsulates it into a single, simulation platform.  Key technology features of OMPTM include:

  • A defined scripting language, allowing OMP to be "programmed" for specific tasks necessary to users or client applications,
  • Fully encapsulated hybridization science functions which precisely predict the DNA hybridization that will result from any specific oligo experiment under a variety different design conditions, including;

    • Single-strand optimal and sub-optimal unimolecular structure prediction, recursive bimolecular hybridization algorithm,
    • Customized numerical analysis code for the solution of multiple coupled hybridization equilibria,
    • DNA secondary structure display,
    • Display of species concentrations as a function of temperature,
    • Interface with the sequence and annotation data in the SNP database,
    • Interface with the Oracle, SQL and MS ACCESS database format,
  • Rich modeling functionality, including capabilities to predict DNA microarray effectiveness, PCR and PCR multiplexed efficiency, and oligo probe and primer interactions (dimerization),
  • A cutting edge peer-to-peer distributed computing architecture which allows OMPTM to run across a cluster or network of PCs, making OMPTM scalable and extremely fast,
  • Cross-platform capability to run on most any commercial Windows, Linux, or Unix machine.


To learn more about our proprietary Oligonucleotide Modeling PlatformTM, please Contact us.

 

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