Visual OMPTM 6.6 Upgrade Released to All Customers
ANN ARBOR, MI – Aug. 28, 2008 – DNA Software, Inc. is pleased to announce the release of Visual OMPTM 6.6, which now contains improved parameters for both DNA dangling ends in RNA:DNA duplexes and closing basepairs.
Most nucleic acid software programs are unable to generate accurate in silico predictions of nucleic acid secondary structure and hybridization because they utilize inaccurate scientific models, rudimentary algorithms, and incomplete sets of thermodynamic parameters. In contrast, DNA Software’s tools generate the most accurate in silico predictions for nucleic acids because they uniquely incorporate (1) an advanced multi-state coupled equilibrium model and folding algorithm, which folds every sequence and accounts for every possible hybridization scenario; and (2) the industry’s most extensive database of nearest neighbor thermodynamic parameters, which includes all parameters from the public domain plus thousands of additional proprietary thermodynamic parameters that were derived in DNA Software’s own wet lab from wide-ranging experimental conditions and structural motifs.
DNA Software is continuously expanding its extensive database of thermodynamic parameters to provide its customers with the best capabilities for the design, simulation, and analysis of nucleic acid-based assays, therapeutics, and technologies. DNA Software’s Visual OMPTM 6 6.6 uniquely contains wet lab-derived thermodynamic parameters for DNA dangling ends in RNA:DNA duplexes and closing basepairs. While other software programs approximate these interactions, Visual OMPTM 6 uniquely and accurately generates in silico predictions based upon experimental measurements. In addition to expert technical support, DNA Software’s customers automatically receive the Visual OMP 6.6 update as part of their annual product license.
About DNA Software, Inc.
DNA Software, Inc. was founded in 2000 to commercialize the advances in nucleic acid chemistry discovered by world-renowned expert Dr. John SantaLucia, Jr. (the company’s Chief Scientific Officer). DNA Software’s technologies have become the standard of excellence for nucleic acid research and diagnostics development.
DNA Software is a unique software company considering that it conducts original wet lab research. The company’s software programs are the most accurate and comprehensive tools available because its advanced algorithms and models are driven by a large database of thousands of diverse, wet lab-derived, experimental results. DNA Software’s tools correctly design and simulate complicated experiments on the first attempt. Customers can simulate thousands of experiments with the software before running a single experiment in a wet lab. Thus, DNA Software’s technologies save customers significant time, resources, and money that would have been wasted on trial-and-error experimentation.
DNA Software offers contract research, custom software development, commercial web applications, and scientific consulting for nucleic acid research. The company also licenses packaged software tools that help scientists quickly and accurately develop new assays, diagnostics, and therapeutics. OMPTM (Oligonucleotide Modeling PlatformTM), the core engine that runs all of DNA Software’s tools, models in silico the folding and hybridization of nucleic acids with exception accuracy. Visual OMPTM is a platform program for the analysis of nucleic acid secondary structure plus the design, simulation, and optimization of probes/primers, RT-PCR, qPCR, Multiplex PCR, Taqman, Beacons, Scorpions, Microarrays, SNP detection, FRET assays, RNAi, LATE-PCR, plus new formats. ThermoBLASTTM quickly and accurately scans DNA, or RNA against large genome databases, identifies all hybridizations under actual reaction conditions, and detects all extensible, off-target amplicons. OMP Developer EditionTM (OMP DETM) and ThermoBLAST Developer EditionTM (TB DETM) bring customizable, command line, high-throughput computing power to large assay design and genome scanning projects or enterprise applications.
The company has expanded its original DNA and RNA-based, molecular biology solutions to include modified nucleotides, oligonucleotide kinetics, and structural biology.
For more information, please contact DNA Software at +1 734 222 9080, info@dnasoftware.com, or www.dnasoftware.com.